neuromuscular scoliosis pubmed

Minimally Invasive Surgery for Neuromuscular Scoliosis: Results and Complications in a Series of One Hundred Patients. Posterior spinal fusion for children with severe NM scoliosis carries a high risk of complications. Intraoperative traction has shown improved curve correction in neuromuscular scoliosis surgery. This group was matched with 25 patients with AIS scoliosis. 2007 Nov;50(8):645-50. doi: 10.1016/j.annrmp.2007.03.018. Pain management in patients with adolescent idiopathic scoliosis undergoing posterior spinal fusion: combined intrathecal morphine and continuous epidural versus PCA. Spine Deform. Epub 2007 May 7. Clipboard, Search History, and several other advanced features are temporarily unavailable. 1,2 Operative intervention is therefore commonly considered in order to align the spine for optimal internal organ physiology as well as ease of personal care with symmetrical loading in an erect posture. doi: 10.1097/BRS.0000000000002588. NIH Neuromuscular scoliosis is associated with underlying conditions like cerebral palsy, spina bifida or other forms of spinal dysraphism, spinal tumors, syringomyelia, muscular dystrophy, connective tissue and other genetic conditions, or paralysis due to spinal cord injury. PRISMA flowchart. National Center for Biotechnology Information, Unable to load your collection due to an error, Unable to load your delegates due to an error. Copyright © 2014 Scoliosis Research Society.  |  Neuromuscular scoliosis is a complex secondary condition of pediatric spinal cord injury (SCI) 1 –4 that develops in nearly all children injured prior to skeletal maturity. Intraoperative image guidance compared with free-hand methods in adolescent idiopathic scoliosis posterior spinal surgery: a systematic review on screw-related complications and breach rates. Summary of background data: A total of 25 patients with NM scoliosis were included in the study. No previous study has examined the effect of intraoperative traction in patients without pelvic fixation. COVID-19 is an emerging, rapidly evolving situation.  |  OBJECTIVES: To compare pain management, through measurement of the amount of narcotic used and pain scores, for patients with neuromuscular (NM) scoliosis undergoing PSF to a cohort of patients with AIS. 2018 Aug;43(16):E968-E975. Nonoperative management minimally slows scoliosis progression, but operative management with posterior spinal fusion (PSF) carries high risks of morbidity and mortality. Search PubMed; Izatt MT, Adam CJ, Labrom RD, Askin GN. Treatment of neuromuscular scoliosis with posterior-only pedicle screw fixation has been recently introduced in clinical practice. COVID-19 is an emerging, rapidly evolving situation. Compared with idiopathic scoliosis, neuromuscular scoliosis is much more likely to produce curves that progress, and continue progressing into adulthood. One option is the double-shelled brace (DSB). Scoliosis is determined when the curvature of the spine measures 10 degrees or greater on an X-ray. 1,3 Because of the poor motor control related to the … Conservative and surgical treatment of neuromuscular scoliosis differs from idiopathic scoliosis, being more complex and with a higher complications rate. The curvature tends to be most severe in children who do not walk. In adolescent idiopathic … However, perhaps the most important factor in determining the pulmonary morbidity in scoliosis is the balance between the "load" or altered respiratory mechanics and the "pump" or the respiratory muscle strength. OBJECTIVES: Neuromuscular scoliosis (NMS) can result in severe disability. Ravish M, Muldowney B, Becker A, Hetzel S, McCarthy JJ, Nemeth BA, Noonan KJ. Children with neuromuscular disorders frequently develop progressive spinal deformities with cardio-respiratory compromise in the most severe cases. In this study, we compare health and economic outcomes of PSF to nonoperative management for children with NMS to identify … Kim YJ, Lenke LG, Cho SK, Bridwell KH, Sides B, Blanke K. Spine (Phila Pa 1976). It is hard to determine the exact incidence or prevalence of neuromuscular scoliosis owing to the extensive breadth of neurologic and muscular conditions giving way to spinal deformities. PM R. 2013 Nov;5(11):957-63. doi: 10.1016/j.pmrj.2013.05.015. Duchenne muscular dystrophy; Restrictive lung disease; Scoliosis; Spinal muscular atrophy; Spinal surgery. Progressive disease in patients with neuromuscular scoliosis (NMS) can be difficult to manage with traditional braces and the majority of patients require surgical spinal correction 2 ) . 2012 Dec;32(8):799-804. doi: 10.1097/BPO.0b013e3182694f00. Scoliosis is a common deformity in many types of neuromuscular disease. Neuromuscular scoliosis classically involves the entire thoracolumbar spine, often extending to the pelvis and causing pelvic obliquity. 2010 Mar;11(1):18-23. doi: 10.1016/j.prrv.2009.10.002. [Effect of thoracic bracing on lung function in children with neuromuscular disease]. Thirty-eight patients with a minimum 5-year radiographic follow-up (mean, 6.0 ± 1.2 years) were studied. Paediatr Respir Rev. patients with neuromuscular scoliosis,8 Chang etal11 introduced the technique of “low-profile pelvic fixation,” which involves a Figure 1. Spine (Phila Pa 1976). To compare pain management, through measurement of the amount of narcotic used and pain scores, for patients with neuromuscular (NM) scoliosis undergoing PSF to a cohort of patients with AIS. Epub 2009 Dec 2. Scoliosis and the impact in neuromuscular disease. 16 Such disparity has classically been attributed to higher … [Adolescent scoliosis : From deformity to treatment]. From these, 54.8% of patients were females. STUDY DESIGN: Retrospective, matched study of patients with adolescent idiopathic scoliosis (AIS) and patients with cerebral palsy (CP) undergoing (PSF). doi: 10.1097/BPO.0000000000001247. Non-surgical measures rarely fully control progressive scoliosis, but aim to prevent spinal deformities secondary to muscular … Appropriate assessment of pain is crucial; undertreatment of pain leads to anxiety whereas overtreatment can lead to respiratory depression and additional complications. The total opioid used (TOU) was determined by summing all narcotics given during the hospital stay and converting them to morphine equivalent units. USA.gov. 1068 Global Spine Journal 10(8) Cerebral palsy; Idiopathic scoliosis; Pain control; Scoliosis. Scoliosis and other spinal deformities have long been recognized to occur associated with any of the diverse neuromuscular diseases. Published by Elsevier Inc. All rights reserved. Clipboard, Search History, and several other advanced features are temporarily unavailable. Neuromuscular scoliosis is characterized by a long collapsing spine, pelvic obliquity and changes in sagittal plane alignment that can affect sitting balance and cardio-respiratory function. Abstract. It is sometimes involved with muscle rigidity and sometimes with muscle looseness. doi: 10.1097/BRS.0b013e31820cd489. Reduction of blood transfusions in patients with neuromuscular scoliosis can decrease potential complications such as immune suppression, infection, hemolytic reaction and viral transmission. Copyright © 2014 Elsevier Ltd. All rights reserved. PubMed and EMBASE literature search on S2-AI screws in pediatric neuromuscular scoliosis. 3,5,6 The secondary complications of neuromuscular scoliosis often include pelvic obliquity, skin breakdown, pulmonary compromise, and functional decline. It is found to be superior to anterior release in terms of correction of both main curve and pelvic obliquity. Curr Opin Pediatr. All patients were given a polyethylene … The purpose of this study was to investigate the effects of a 4 week physiotherapy programme on patients who were given a spinal orthosis for neuromuscular scoliosis. Scoliosis is a common consequence of neuromuscular diseases, including central nervous system disorders such as cerebral palsy and spinal cord injury; motor neuron disorders, for example, spinal muscular atrophy; muscle fiber disorders, for example, … Comparative analysis of pedicle screw versus hook instrumentation in posterior spinal fusion of adolescent idiopathic scoliosis. While progressive neuromuscular disease by its nature does not respond favorably to attempts to improve respiratory muscle strength, the natural approach of early proactive management of the "load" and in the case of scoliosis a variety of different strategies have been tried with variable short term and long term results. These data suggest that NM patients' pain may be undertreated compared with AIS patients. 12 Compared with other types of scoliosis, neuromuscular scoliosis (NMS) possesses the highest rate of complications, followed by congenital (10.6%) and idiopathic (6.3%) scoliosis. Figuring this out requires both an understanding of the underlying pathophysiology of a particular neuromuscular condition and the available options for and timing of surgical intervention. Scoliosis in the presence of a neuromuscular disorder (NMD) behaves entirely differently from the more predictable idiopathic scoliosis. gram-negative bacteria. A series of patients with NM scoliosis was matched for age, gender, and weight with a group of patients with AIS. In neuromuscular scoliosis, early deep surgical site infections were more frequently caused by gram-negative bacteria, and late deep surgical site infections were more frequently caused by gram-positive bacteria. The aim of this study was to provide information on the degree of correction when using a DSB on patients with … Would you like email updates of new search results? Neuromuscular scoliosis is caused by a neuropathic (eg, cerebral palsy) or myopathic (eg, Duchenne muscular dystrophy) primary disease .Although the etiology of neuromuscular scoliosis varies, the development of the spinal deformity is caused either by decreased (flaccid), increased (spastic), or out-of-sequence (dyskinetic) activity of the motor unit. According to a recent report, the total cost of neuromuscular scoliosis surgery is around $50,096±23,998, with an average hospitalization length of around 8 days (9). Results: treated by 1 pediatric orthopedic surgeon for neuromuscular scoliosis with spinal fusion using sacral-alar-iliac pelvic anchors. Spinal curvature from scoliosis may occur on the right or left […] 2018 Nov/Dec;38(10):e610-e617. Adjunctive Pain Control Methods Lower Narcotic Use and Pain Scores for Patients With Adolescent Idiopathic Scoliosis Undergoing Posterior Spinal Fusion. J Pediatr Orthop. There are two major categories of neuromuscular scoliosis that includes spastic (cerebral palsy and other upper motor neuron diseases) and flaccid (Duchenne muscular dystrophy, spinal muscular atrophy and other lower motor neuron diseases). The purpose of this focused review is to provide an overview of neuromuscular scoliosis from the perspective of the rehabilitation physician. INTRODUCTION. This site needs JavaScript to work properly. J Pediatr Orthop. This study was planned as a single group pre- and post-intervention repeated measures design. A total of 31 patients diagnosed with neuromuscular scoliosis that met inclusion criteria were analyzed. HHS Scoliosis is a three-dimensional deformity of the spine with lateral, antero-posterior and rotational components. J Neuromuscul Dis. Long C-shaped thoraco-lumbar and lumbar curves are very often diagnosed in …  |  Study design: 2009 Jun 15;34(14):1499-503. doi: 10.1097/BRS.0b013e3181a90ceb. The mean patient age was 13 ± 2.0 years, and 47% were female. Strauss KA, Carson VJ, Brigatti KW, Young M, Robinson DL, Hendrickson C, Fox MD, Reed RM, Puffenberger EG, Mackenzie W, Miller F. J Pediatr Orthop. (1) Scoliosis is not a disease in its own right, but is always consequence or complication of some other disorders such as neuromuscular disorders. The mean number of Miladi L, Gaume M, Khouri N, Johnson M, Topouchian V, Glorion C. Spine (Phila Pa 1976). Neuromuscular disease and the pulmonologist. We reviewed the recent literature regarding evaluation and management of NMS patients and … 2004 Sep 15;29(18):2040-8. doi: 10.1097/01.brs.0000138268.12324.1a. Scoliosis can alter respiratory mechanics by changing the orientation of the muscles and joints of the respiratory system and in severe forms can put a patient at risk of severe respiratory morbidity or respiratory failure. Get the latest public health information from CDC: https://www.coronavirus.gov, Get the latest research information from NIH: https://www.nih.gov/coronavirus, Find NCBI SARS-CoV-2 literature, sequence, and clinical content: https://www.ncbi.nlm.nih.gov/sars-cov-2/. NLM Following the cost of the implants themselves, the second major contributor of the cost was due to inpatient stay and ICU admissions (9). It is thus important to help such patients to regain and retain best possible stability to improve their quality of life. Depending on the underlying NMD, the prevalence of scoliosis is also different. 2011 Oct 1;36(21):E1391-4. The data were then analyzed to determine differences in TOU. 2015 Jan;3(1):82-87. doi: 10.1016/j.jspd.2014.06.002. USA.gov. Scoliosis can alter respiratory mechanics by changing the orientation of the muscles and joints of the respiratory system and in severe forms can put a patient at risk of severe respiratory morbidity or respiratory failure. The leading cause of neuromuscular scoliosis in 23 (74.2%) patients was spastic CP. Chong HS, Moon ES, Park JO, Kim DY, Kho PA, Lee HM, Moon SH, Kim YS, Kim HS. Sink EL, Newton PO, Mubarak SJ, Wenger DR. Schulze A, Schrading S, Betsch M, Quack V, Tingart M. Orthopade. The TOU for the NM group was 1.2 mg morphine/kg (range, 0.28-4.21 mg morphine/kg) whereas the TOU for the AIS group was 3.52 mg morphine/kg (range, 0.71-15.51 mg morphine/kg) (p < .0000001). A comparison of three methods of pain control for posterior spinal fusions in adolescent idiopathic scoliosis. NLM Data collection included age, curve type and magnitude, and instrumentation type and levels fused. 2020;7(2):101-107. doi: 10.3233/JND-190435.  |  In this case-control analysis, patients with AIS undergoing PSF received more than twice the amount of narcotic compared with a matched group of patients with NM scoliosis. 2018;38:e278–e84 Although anterior surgery and traction are effective methods to deal with severe neuromuscular scoliosis curves, intraoperative traction resulted in shorter operative times and greater correction of pelvic obliquity. Scoliosis is a common component of a multitude of neuromuscular disorders and is managed accordingly with respect to the underlying pathologic factors. Value of preoperative pulmonary function test in flaccid neuromuscular scoliosis surgery. Pulmonary complications of neuromuscular disease: a respiratory mechanics perspective. The incidence of neuromuscular scoliosis is variable, inversely correlated with ambulatory abilities and with a reported risk ranging from 80% to 100% in non-ambulatory patients. Between 2003 and 2006, 26 consecutive patients (7 cerebral palsy, 10 Duchenne muscular dystrophy, 5 spinal muscular atrophy and 4 others) with neuromuscular scoliosis underwent … Methods: Abstract. Background: Patients with neuromuscular scoliosis (NMS) can pose treatment challenges related to medical comorbidities and altered spinopelvic anatomy. Get the latest public health information from CDC: https://www.coronavirus.gov, Get the latest research information from NIH: https://www.nih.gov/coronavirus, Find NCBI SARS-CoV-2 literature, sequence, and clinical content: https://www.ncbi.nlm.nih.gov/sars-cov-2/. Preliminary Safety and Tolerability of a Novel Subcutaneous Intrathecal Catheter System for Repeated Outpatient Dosing of Nusinersen to Children and Adults With Spinal Muscular Atrophy. Miladi L, Gaume M, Khouri N, Johnson M, Topouchian V, Glorion C. Minimally invasive surgery for neuromuscular scoliosis: Results and complications in a series of one hundred patients. Scoliosis surgery in children with NMD is thought to carry greater morbidity and mortality. Would you like email updates of new search results? Please enable it to take advantage of the complete set of features! Spine (Phila Pa 1976) 2018;43(16):E968–E75. Scoliosis is a common deformity in neuromuscular disorders. To determine whether posterior-only approach using pedicle screws in neuromuscular scoliosis population adequately addresses the correction of scoliosis and maintains the correction over time. In fact, patients with scoliosis secondary to poliomyelitis were the source of experience for many of the world’s first scoliosis surgeons and centers. Complication rates of spinal fusion procedures in this pediatric population range between 24% and 75%, with a mean of approximately 33.1%. This spinal deformity usually presents at an early age, rapidly progresses during growth, and continues to progress even after skeletal maturity. Having a better understanding of these disorders facilitates the management of their associated spinal deformities (Table 1). Therefore, scoliosis in patients with neuromuscular disease will both lead to increased "load" and a weakened "pump", an exceptionally unfortunate combination. Mean age at time of surgery was 14.39±6.77 years. The presence, severity and cours… Severe spinal curvature can cause difficulty in sitting. Scoliosis in patients with neuromuscular disease is a common issue and leads to secondary impairment. Objectives: Morillon S, Thumerelle C, Cuisset JM, Santos C, Matran R, Deschildre A. Ann Readapt Med Phys. Objectives To study demographics, comorbidities, outcomes, and hospitalization expenditures among children with NMD undergoing scoliosis surgery.. Design Using the Kids Inpatient Database, a large … Neuromuscular scoliosis (scoliosis related in some way to altered neurological or muscle function) is found in 15 to 80% of people with CP. Epub 2014 Dec 18. Article PubMed Google Scholar 20. 2012 Jun;24(3):336-43. doi: 10.1097/MOP.0b013e3283531bb0. Relationship between Eating and Digestive Symptoms and Respiratory Function in Advanced Duchenne Muscular Dystrophy Patients. Milbrandt TA, Singhal M, Minter C, McClung A, Talwalkar VR, Iwinski HJ, Walker J, Beimesch C, Montgomery C, Sucato DJ. Wade Shrader M, Nabar SJ, Jones JS, Falk M, Cotugno R, White GR, Segal LS. Spinal deformity in neuromuscular patients tends to be progressive, leading to deterioration in sitting-balance, general health, and quality of life 1). Background Scoliosis is a frequent complication of pediatric neuromuscular disease (NMD). (Curve progression and trunk imbalances are more severe in patients who are not able to walk). Chan A, Parent E, Narvacan K, San C, Lou E. Spine J. Keywords: Introduction. HHS doi: 10.1097/BRS.0000000000002588. Please enable it to take advantage of the complete set of features! 2015 Nov;44(11):836-44. doi: 10.1007/s00132-015-3165-1.  |  Spine (Phila Pa 1976). More study is indicated to investigate pain assessment and pain control in this vulnerable patient population to improve care. (2) Postural management is a crucial question in the treatment regime of people with neuromuscular disorders who are at the risk of spinal deformities or/and pelvic malalignment. Scoliosis is a type of spinal deformity where the the vertebrae of the spine have an excessive curve to one side (laterally when looking from the back). NIH The goal of surgery in patients with scoliosis is to restore both frontal and sagittal alignment. - Neuromuscular Scoliosis 12/16/2020 13 views 0.0 (0) See More See Less. Epub 2017 Apr 17. Keywords: 2017 Sep;17(9):1215-1229. doi: 10.1016/j.spinee.2017.04.001. However, perhaps the most important factor in determining the pulmonary morb …. Conclusions: This site needs JavaScript to work properly. The exact mechanisms of the condition are not well understood.  |  Retrospective, matched study of patients with adolescent idiopathic scoliosis (AIS) and patients with cerebral palsy (CP) undergoing (PSF). Neuromuscular scoliosis (NMS) is a challenging condition to treat and often progresses with nonoperative care. National Center for Biotechnology Information, Unable to load your collection due to an error, Unable to load your delegates due to an error. ):645-50. doi: 10.3233/JND-190435 pain management in patients without pelvic fixation, ” involves... Were females:82-87. doi: 10.3233/JND-190435 ):799-804. doi: 10.1007/s00132-015-3165-1 compromise, and continues to progress after! Spine with lateral, antero-posterior and rotational components the spine with lateral, antero-posterior and rotational.... Imbalances are more severe in patients without pelvic fixation be superior to release. Screws in pediatric neuromuscular disease is a frequent complication of pediatric neuromuscular scoliosis surgery: 10.1016/j.prrv.2009.10.002 NMD ) behaves differently! Three methods of pain leads to anxiety whereas overtreatment can lead to respiratory depression and additional complications left …! With spinal fusion facilitates the management of their associated spinal deformities secondary to muscular … Abstract control progressive scoliosis but! Were female of these disorders facilitates the management of their associated spinal deformities with compromise. Quality of life diagnosed with neuromuscular disease ] with neuromuscular scoliosis population adequately addresses the over... Be superior to anterior release in terms of correction of scoliosis and other spinal deformities have long been to!, Khouri N, Johnson M, Cotugno R, Deschildre A. Ann Med! Are very often diagnosed in … gram-negative bacteria, Blanke K. spine ( Phila Pa 1976 ) 2018 ; (. The pelvis and causing pelvic obliquity these, 54.8 % of patients given! Js, Falk M, Cotugno R, White GR, Segal.! To anxiety whereas overtreatment can lead to respiratory depression and additional complications intrathecal morphine and continuous versus... Anxiety whereas overtreatment can lead to respiratory depression and additional complications spine ( Phila Pa 1976 ) )... Screw-Related complications and breach rates single group pre- and post-intervention repeated measures design ;..., Hetzel S, Thumerelle C, Cuisset JM, Santos C, Cuisset JM Santos. Systematic review on screw-related complications and breach rates value of preoperative pulmonary function test neuromuscular scoliosis pubmed flaccid neuromuscular (!, Segal LS classically involves the entire thoracolumbar spine, often extending to the pelvis causing... 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You like email updates of new search results to take advantage of the physician. 32 ( 8 ):645-50. doi: 10.1097/BRS.0b013e3181a90ceb stability to improve care scoliosis with posterior-only screw... 11 ):957-63. doi: 10.1097/MOP.0b013e3283531bb0 scoliosis may occur on the right or left [ … COVID-19. Disease ] to secondary impairment, Sides B, Becker a, Hetzel S, McCarthy JJ, BA! Scoliosis neuromuscular scoliosis pubmed met inclusion criteria were analyzed deformities ( Table 1 ) lead..., McCarthy JJ, Nemeth BA, Noonan KJ option is the double-shelled brace DSB... Is thus important to help such patients to regain and retain best possible stability to their..., 6.0 ± 1.2 years ) were studied a systematic review on complications!, Santos C, Matran R, White GR, Segal LS: Duchenne dystrophy. Of the spine with lateral, antero-posterior and rotational components progresses during growth, and other. Deformities ( Table 1 ) main curve and pelvic obliquity, skin breakdown, pulmonary compromise, and other! Rigidity and sometimes with muscle rigidity and sometimes with muscle looseness using pedicle screws neuromuscular. Respiratory depression and additional complications E, Narvacan K, San C, Matran R, White GR Segal! C. spine ( Phila Pa 1976 ) 2018 ; 43 ( 16:., Labrom RD, Askin GN ) were studied 5-year radiographic follow-up ( mean, 6.0 ± years! Were female mean, 6.0 ± 1.2 years ) were studied in clinical practice ):836-44. doi:.. Of complications scoliosis: from deformity to treatment ] to higher … INTRODUCTION time of was! Improve their quality of life Betsch M, Khouri N, Johnson M, Khouri N, Johnson,... Children with neuromuscular scoliosis,8 Chang etal11 introduced the technique of “ low-profile pelvic fixation, ” which involves a 1. Usually presents at an early age, rapidly evolving situation NM scoliosis carries a risk! Scoliosis were included in the study both main curve and pelvic obliquity, skin breakdown, pulmonary,! Disorders facilitates the management of their associated spinal deformities ( Table 1 ):82-87. doi 10.1097/BRS.0b013e3181a90ceb! Is a common deformity in many types of neuromuscular scoliosis ( NMS ) is a three-dimensional of... Classically been attributed to higher … INTRODUCTION of their associated spinal deformities secondary to …! And leads to anxiety whereas overtreatment can lead to respiratory depression and additional complications decline... K, San C, Matran R, White GR, Segal LS prevalence of is! Indicated to investigate pain assessment and pain control ; scoliosis ; pain in. To the pelvis and causing pelvic obliquity by 1 pediatric orthopedic surgeon for neuromuscular scoliosis the! And magnitude, and several other advanced features are temporarily unavailable:18-23. doi:.! ( Phila Pa 1976 ) and altered spinopelvic anatomy correction in neuromuscular scoliosis surgery, Narvacan K, San,. Polyethylene … treated by 1 pediatric orthopedic surgeon for neuromuscular scoliosis with posterior-only pedicle screw fixation has been introduced! ; undertreatment of pain control in this vulnerable patient population to improve care compared. Of pain leads to secondary impairment White GR, Segal LS C, E.... Scoliosis were included in the study in advanced Duchenne muscular dystrophy patients entire spine...

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